diff --git a/gnu-system.am b/gnu-system.am
index ffb18e8573..20d3e67662 100644
--- a/gnu-system.am
+++ b/gnu-system.am
@@ -232,7 +232,6 @@ dist_patch_DATA =						\
   gnu/packages/patches/glibc-bootstrap-system.patch		\
   gnu/packages/patches/glibc-ldd-x86_64.patch			\
   gnu/packages/patches/glibc-make-4.0.patch			\
-  gnu/packages/patches/glibc-no-ld-so-cache.patch		\
   gnu/packages/patches/grub-gets-undeclared.patch		\
   gnu/packages/patches/gstreamer-0.10-bison3.patch		\
   gnu/packages/patches/gstreamer-0.10-silly-test.patch		\
diff --git a/gnu/packages/base.scm b/gnu/packages/base.scm
index 0fa7b3f137..d32f617ceb 100644
--- a/gnu/packages/base.scm
+++ b/gnu/packages/base.scm
@@ -365,9 +365,17 @@ archives.")
             (sha256
              (base32
               "18spla703zav8dq9fw7rbzkyv9qfisxb26p7amg1x3wjh7iy3d1c"))
+            (snippet
+             ;; Disable 'ldconfig' and /etc/ld.so.cache.  The latter is
+             ;; required on LFS distros to avoid loading the distro's libc.so
+             ;; instead of ours.
+             '(substitute* "sysdeps/unix/sysv/linux/configure"
+                (("use_ldconfig=yes")
+                 "use_ldconfig=no")))
+            (modules '((guix build utils)))
+            (imported-modules modules)
             (patches (map search-patch
-                          '("glibc-no-ld-so-cache.patch"
-                            "glibc-ldd-x86_64.patch"
+                          '("glibc-ldd-x86_64.patch"
                             "glibc-make-4.0.patch")))))
    (build-system gnu-build-system)
 
diff --git a/gnu/packages/patches/glibc-no-ld-so-cache.patch b/gnu/packages/patches/glibc-no-ld-so-cache.patch
deleted file mode 100644
index 75fff50b47..0000000000
--- a/gnu/packages/patches/glibc-no-ld-so-cache.patch
+++ /dev/null
@@ -1,53 +0,0 @@
-Disable attempts to use the system-wide /etc/ld.so.cache.  This is
-required on LFS distros to avoid loading the distro's libc.so instead
-of ours.
-
-Patch from Nixpkgs.  Idea by Eelco Dolstra, initial patch by Jack
-Cummings, minor fixups by Shea Levy.
-
-diff -Naur glibc-2.13-orig/elf/ldconfig.c glibc-2.13/elf/ldconfig.c
---- glibc-2.13-orig/elf/ldconfig.c	2011-01-17 23:34:07.000000000 -0500
-+++ glibc-2.13/elf/ldconfig.c	2012-04-10 23:28:45.957492340 -0400
-@@ -51,7 +51,7 @@
- #endif
- 
- #ifndef LD_SO_CONF
--# define LD_SO_CONF SYSCONFDIR "/ld.so.conf"
-+# define LD_SO_CONF PREFIX "/etc/ld.so.conf"
- #endif
- 
- /* Get libc version number.  */
-
---- glibc-2.16.0/elf/Makefile	2012-06-30 21:12:34.000000000 +0200
-+++ glibc-2.16.0/elf/Makefile	2012-11-12 23:52:21.000000000 +0100
-@@ -415,12 +415,12 @@ $(objpfx)ldconfig: $(ldconfig-modules:%=
- 
- $(objpfx)pldd: $(pldd-modules:%=$(objpfx)%.o)
- 
--SYSCONF-FLAGS := -D'SYSCONFDIR="$(sysconfdir)"'
--CFLAGS-ldconfig.c = $(SYSCONF-FLAGS) -D'LIBDIR="$(libdir)"' \
-+PREFIX-FLAGS := -D'PREFIX="$(sysconfdir)"'
-+CFLAGS-ldconfig.c = $(PREFIX-FLAGS) -D'LIBDIR="$(libdir)"' \
- 		    -D'SLIBDIR="$(slibdir)"' -DIS_IN_ldconfig=1
--CFLAGS-dl-cache.c = $(SYSCONF-FLAGS)
--CFLAGS-cache.c = $(SYSCONF-FLAGS)
--CFLAGS-rtld.c = $(SYSCONF-FLAGS)
-+CFLAGS-dl-cache.c = $(PREFIX-FLAGS)
-+CFLAGS-cache.c = $(PREFIX-FLAGS)
-+CFLAGS-rtld.c = $(PREFIX-FLAGS)
- 
- CPPFLAGS-.os += $(if $(filter $(@F),$(patsubst %,%.os,$(all-rtld-routines))),\
- 		     -DNOT_IN_libc=1 -DIS_IN_rtld=1 -DIN_LIB=rtld)
-
-diff -Naur glibc-2.13-orig/sysdeps/generic/dl-cache.h glibc-2.13/sysdeps/generic/dl-cache.h
---- glibc-2.13-orig/sysdeps/generic/dl-cache.h	2011-01-17 23:34:07.000000000 -0500
-+++ glibc-2.13/sysdeps/generic/dl-cache.h	2012-04-10 23:28:20.077488815 -0400
-@@ -29,7 +29,7 @@
- #endif
- 
- #ifndef LD_SO_CACHE
--# define LD_SO_CACHE SYSCONFDIR "/ld.so.cache"
-+# define LD_SO_CACHE PREFIX "/etc/ld.so.cache"
- #endif
- 
- #ifndef add_system_dir