diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index e0134da550..0704e6df80 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -11363,13 +11363,13 @@ reference point and sorted by a user defined feature.")
 (define-public r-sesame
   (package
     (name "r-sesame")
-    (version "1.20.0")
+    (version "1.22.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "sesame" version))
               (sha256
                (base32
-                "0yh4mrsj3pqhjkrq5dwmcpcqwixs0pmjy7dfa3cr0mf52fgzcvmr"))))
+                "0qz4vhz1iczz4n4wigzqkmkbsvq5ql04x1gawxv4f8ii61npp0h4"))))
     (properties `((upstream-name . "sesame")))
     (build-system r-build-system)
     (propagated-inputs (list r-biocfilecache