diff --git a/guix/self.scm b/guix/self.scm
index c0de14b79a..ca67f653fa 100644
--- a/guix/self.scm
+++ b/guix/self.scm
@@ -650,17 +650,22 @@ load path."
   (program-file "guix-command"
                 #~(begin
                     (set! %load-path
-                      (cons (string-append #$module-directory
-                                           "/share/guile/site/"
-                                           (effective-version))
-                            %load-path))
+                      (append (list (string-append #$module-directory
+                                                   "/share/guile/site/"
+                                                   (effective-version))
+                                    (string-append #$guile "/share/guile/"
+                                                   (effective-version)))
+                              %load-path))
 
                     (set! %load-compiled-path
-                      (cons (string-append #$module-directory
-                                           "/lib/guile/"
-                                           (effective-version)
-                                           "/site-ccache")
-                            %load-compiled-path))
+                      (append (list (string-append #$module-directory
+                                                   "/lib/guile/"
+                                                   (effective-version)
+                                                   "/site-ccache")
+                                    (string-append #$guile "/lib/guile/"
+                                                   (effective-version)
+                                                   "/ccache"))
+                              %load-compiled-path))
 
                     ;; To maximize the chances that locales are set up right
                     ;; out-of-the-box, bundle "common" UTF-8 locales.