diff --git a/guix/build-system/r.scm b/guix/build-system/r.scm
index 7ab4db82b6..37786f02a0 100644
--- a/guix/build-system/r.scm
+++ b/guix/build-system/r.scm
@@ -60,7 +60,7 @@ release corresponding to NAME and VERSION."
                          "/src/contrib/"
                          name "_" version ".tar.gz")
           ;; TODO: use %bioconductor-version from (guix import cran)
-          (string-append "https://bioconductor.org/packages/3.18"
+          (string-append "https://bioconductor.org/packages/3.19"
                          type-url-part
                          "/src/contrib/"
                          name "_" version ".tar.gz"))))
diff --git a/guix/import/cran.scm b/guix/import/cran.scm
index c4c42836ee..fa9fffe274 100644
--- a/guix/import/cran.scm
+++ b/guix/import/cran.scm
@@ -198,9 +198,9 @@ package definition."
 (define %cran-canonical-url "https://cran.r-project.org/package=")
 (define %bioconductor-url "https://bioconductor.org/packages/")
 
-;; The latest Bioconductor release is 3.18.  Bioconductor packages should be
+;; The latest Bioconductor release is 3.19.  Bioconductor packages should be
 ;; updated together.
-(define %bioconductor-version "3.18")
+(define %bioconductor-version "3.19")
 
 (define* (bioconductor-packages-list-url #:optional type)
   (string-append "https://bioconductor.org/packages/"