diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 71f93f43c1..14cbe6852f 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -3300,13 +3300,13 @@ Shiny-based display methods for Bioconductor objects.")
 (define-public r-limma
   (package
     (name "r-limma")
-    (version "3.48.0")
+    (version "3.48.1")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "limma" version))
               (sha256
                (base32
-                "1mkpl2b1ksylc6dih4a6kgjjia8advikzmqmv762j4r7gya950pf"))))
+                "1wscxvhrz16sfa0qwk9anxqjy1vgvqmq6ia9gx6pwpga8qzwn5bi"))))
     (build-system r-build-system)
     (home-page "http://bioinf.wehi.edu.au/limma")
     (synopsis "Package for linear models for microarray and RNA-seq data")