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@ -1408,6 +1408,42 @@ data. In addition, provides numerous plotting functions for commonly
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used visualizations.")
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(license license:artistic2.0)))
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(define-public r-deepsnv
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(package
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(name "r-deepsnv")
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(version "1.36.0")
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(source (origin
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(method url-fetch)
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(uri (bioconductor-uri "deepSNV" version))
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(sha256
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(base32
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"1lbvx9liql8fkb4y020kwpgp61vzg67cy640dc4kybglcw9dx6j0"))))
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(properties `((upstream-name . "deepSNV")))
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(build-system r-build-system)
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(inputs
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`(("zlib" ,zlib)))
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(propagated-inputs
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`(("r-biostrings" ,r-biostrings)
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("r-genomicranges" ,r-genomicranges)
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("r-iranges" ,r-iranges)
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("r-rhtslib" ,r-rhtslib)
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("r-summarizedexperiment" ,r-summarizedexperiment)
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("r-variantannotation" ,r-variantannotation)
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("r-vgam" ,r-vgam)))
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(home-page "https://github.com/gerstung-lab/deepSNV/")
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(synopsis "Detection of subclonal SNVs in deep sequencing data")
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(description
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"This package provides quantitative variant callers for detecting
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subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments.
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The deepSNV algorithm is used for a comparative setup with a control experiment
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of the same loci and uses a beta-binomial model and a likelihood ratio test to
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discriminate sequencing errors and subclonal SNVs. The shearwater algorithm
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computes a Bayes classifier based on a beta-binomial model for variant calling
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with multiple samples for precisely estimating model parameters - such as local
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error rates and dispersion - and prior knowledge, e.g. from variation data
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bases such as COSMIC.")
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(license license:gpl3)))
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(define-public r-delayedarray
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(package
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(name "r-delayedarray")
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