diff --git a/gnu/local.mk b/gnu/local.mk
index 02aa555541..493e10698a 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1225,7 +1225,9 @@ dist_patch_DATA =						\
   %D%/packages/patches/gnutls-cross.patch			\
   %D%/packages/patches/gnutls-guile-eintr-eagain.patch		\
   %D%/packages/patches/gobject-introspection-absolute-shlib-path.patch \
+  %D%/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch \
   %D%/packages/patches/gobject-introspection-cc.patch		\
+  %D%/packages/patches/gobject-introspection-cc-1.72.patch	\
   %D%/packages/patches/gobject-introspection-girepository.patch	\
   %D%/packages/patches/go-fix-script-tests.patch			\
   %D%/packages/patches/go-github-com-golang-snappy-32bit-test.patch \
diff --git a/gnu/packages/glib.scm b/gnu/packages/glib.scm
index 820a44cbde..32220ee69b 100644
--- a/gnu/packages/glib.scm
+++ b/gnu/packages/glib.scm
@@ -546,6 +546,26 @@ provide bindings to call into the C library.")
       ;; For tools.
       license:gpl2+))))
 
+(define-public gobject-introspection-next
+  (package
+    (inherit gobject-introspection)
+    (name "gobject-introspection")
+    (version "1.73.1")
+    (source (origin
+              (method url-fetch)
+              (uri (string-append "mirror://gnome/sources/"
+                                  "gobject-introspection/" (version-major+minor version)
+                                  "/gobject-introspection-" version ".tar.xz"))
+              (sha256
+               (base32 "1gkbx32as3v2286w7k3j24fwhkxj6brr49881m2zavxamfwxdm34"))
+              (patches (search-patches
+                        "gobject-introspection-cc-1.72.patch"
+                        "gobject-introspection-girepository.patch"
+                        "gobject-introspection-absolute-shlib-path-1.72.patch"))))
+    (propagated-inputs
+     (modify-inputs (package-propagated-inputs gobject-introspection)
+       (replace "glib" glib-next)))))
+
 (define intltool
   (package
     (name "intltool")
diff --git a/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch b/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch
new file mode 100644
index 0000000000..8bb86467c0
--- /dev/null
+++ b/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch
@@ -0,0 +1,173 @@
+Names of libraries included in typelib files are opened by dlopen.
+Here we add the full path.
+
+This patch was provided by Luca Bruno <lucabru@src.gnome.org>,
+for 'gobject-introspection' 1.40.0 in Nix.
+
+It has since been updated to work with newer versions of
+gobject-introspection.
+
+diff --git a/giscanner/scannermain.py b/giscanner/scannermain.py
+index 1d39ab84..e12ed24e 100644
+--- a/giscanner/scannermain.py
++++ b/giscanner/scannermain.py
+@@ -95,6 +95,39 @@ def get_windows_option_group(parser):
+     return group
+ 
+ 
++def _get_default_fallback_libpath():
++    # Newer multiple-output-optimized stdenv has an environment variable
++    # $outputLib which in turn specifies another variable which then is used as
++    # the destination for the library contents (${!outputLib}/lib).
++    store_path = os.environ.get(os.environ.get("outputLib")) if "outputLib" in os.environ else None
++    if store_path is None:
++        outputs = os.environ.get("outputs", "out").split()
++        if "lib" in outputs:
++            # For multiple output derivations let's try whether there is a $lib
++            # environment variable and use that as the base store path.
++            store_path = os.environ.get("lib")
++        elif "out" in outputs:
++            # Otherwise we have a single output derivation, so the libraries
++            # most certainly will end up in "$out/lib".
++            store_path = os.environ.get("out")
++
++    if store_path is not None:
++        # Even if we have a $lib as output, there still should be a $lib/lib
++        # directory.
++        return os.path.join(store_path, 'lib')
++    else:
++        # If we haven't found a possible scenario, let's return an empty string
++        # so that the shared library won't be prepended with a path.
++        #
++        # Note that this doesn't mean that all hope is lost, because after all
++        # we can still use --fallback-library-path to set one.
++        #
++        # Also, we're not returning None, because that would make it very
++        # difficult to disable adding fallback paths altogether using something
++        # like: --fallback-library-path=""
++        return ""
++
++
+ def _get_option_parser():
+     parser = optparse.OptionParser('%prog [options] sources',
+                                    version='%prog ' + giscanner.__version__)
+@@ -220,6 +253,10 @@ match the namespace prefix.""")
+     parser.add_option("", "--compiler",
+                       action="store", dest="compiler", default=None,
+                       help="the C compiler to use internally")
++    parser.add_option("", "--fallback-library-path",
++                      action="store", dest="fallback_libpath",
++                      default=_get_default_fallback_libpath(),
++                      help="Path to prepend to unknown shared libraries")
+ 
+     group = get_preprocessor_option_group(parser)
+     parser.add_option_group(group)
+diff --git a/giscanner/shlibs.py b/giscanner/shlibs.py
+index 9f8ab5df..8aa37c99 100644
+--- a/giscanner/shlibs.py
++++ b/giscanner/shlibs.py
+@@ -57,6 +57,14 @@ def _ldd_library_pattern(library_name):
+     $""" % re.escape(library_name), re.VERBOSE)
+ 
+ 
++def _ldd_library_guix_pattern(library_name):
++    store_dir = re.escape(
++      os.environ.get("NIX_STORE", default="/gnu/store")
++    )
++    pattern = r'(%s(?:/[^/]*)+lib%s[^A-Za-z0-9_-][^\s\(\)]*)'
++    return re.compile(pattern % (store_dir, re.escape(library_name)))
++
++
+ # This is a what we do for non-la files. We assume that we are on an
+ # ELF-like system where ldd exists and the soname extracted with ldd is
+ # a filename that can be opened with dlopen().
+@@ -108,7 +116,8 @@ def _resolve_non_libtool(options, binary, libraries):
+             output = output.decode("utf-8", "replace")
+ 
+         shlibs = resolve_from_ldd_output(libraries, output)
+-        return list(map(sanitize_shlib_path, shlibs))
++        fallback_libpath = options.fallback_libpath or "";
++        return list(map(lambda p: os.path.join(fallback_libpath, p), map(sanitize_shlib_path, shlibs)))
+ 
+ 
+ def sanitize_shlib_path(lib):
+@@ -117,19 +126,18 @@ def sanitize_shlib_path(lib):
+     # In case we get relative paths on macOS (like @rpath) then we fall
+     # back to the basename as well:
+     # https://gitlab.gnome.org/GNOME/gobject-introspection/issues/222
+-    if sys.platform == "darwin":
+-        if not os.path.isabs(lib):
+-            return os.path.basename(lib)
+-        return lib
+-    else:
++
++    # Always use absolute paths if available
++    if not os.path.isabs(lib):
+         return os.path.basename(lib)
++    return lib
+ 
+ 
+ def resolve_from_ldd_output(libraries, output):
+     patterns = {}
+     for library in libraries:
+         if not os.path.isfile(library):
+-            patterns[library] = _ldd_library_pattern(library)
++            patterns[library] = (_ldd_library_pattern(library), _ldd_library_guix_pattern(library))
+     if len(patterns) == 0:
+         return []
+ 
+@@ -141,8 +149,12 @@ def resolve_from_ldd_output(libraries, output):
+         if line.endswith(':'):
+             continue
+         for word in line.split():
+-            for library, pattern in patterns.items():
+-                m = pattern.match(word)
++            for library, (pattern, guix_pattern) in patterns.items():
++                store_dir = os.environ.get("NIX_STORE", default="/gnu/store")
++                if line.find(store_dir) != -1:
++                    m = guix_pattern.match(word)
++                else:
++                    m = pattern.match(word)
+                 if m:
+                     del patterns[library]
+                     shlibs.append(m.group())
+diff --git a/giscanner/utils.py b/giscanner/utils.py
+index 31c7ea48..630002a8 100644
+--- a/giscanner/utils.py
++++ b/giscanner/utils.py
+@@ -114,16 +114,11 @@ def extract_libtool_shlib(la_file):
+     if dlname is None:
+         return None
+ 
+-    # Darwin uses absolute paths where possible; since the libtool files never
+-    # contain absolute paths, use the libdir field
+-    if platform.system() == 'Darwin':
+-        dlbasename = os.path.basename(dlname)
+-        libdir = _extract_libdir_field(la_file)
+-        if libdir is None:
+-            return dlbasename
+-        return libdir + '/' + dlbasename
+-    # Older libtools had a path rather than the raw dlname
+-    return os.path.basename(dlname)
++    dlbasename = os.path.basename(dlname)
++    libdir = _extract_libdir_field(la_file)
++    if libdir is None:
++        return dlbasename
++    return libdir + '/' + dlbasename
+ 
+ 
+ # Returns arguments for invoking libtool, if applicable, otherwise None
+diff --git a/tests/scanner/test_shlibs.py b/tests/scanner/test_shlibs.py
+index a8337c60..7f123103 100644
+--- a/tests/scanner/test_shlibs.py
++++ b/tests/scanner/test_shlibs.py
+@@ -40,7 +40,8 @@ class TestLddParser(unittest.TestCase):
+ 
+         self.assertEqual(
+             sanitize_shlib_path('/foo/bar'),
+-            '/foo/bar' if sys.platform == 'darwin' else 'bar')
++            # Always use an absolute filename for Guix
++            '/foo/bar')
+ 
+     def test_unresolved_library(self):
+         output = ''
diff --git a/gnu/packages/patches/gobject-introspection-cc-1.72.patch b/gnu/packages/patches/gobject-introspection-cc-1.72.patch
new file mode 100644
index 0000000000..d3b1df82af
--- /dev/null
+++ b/gnu/packages/patches/gobject-introspection-cc-1.72.patch
@@ -0,0 +1,15 @@
+Use gcc as the default C compiler if CC is not set.
+
+diff --git a/giscanner/__init__.py b/giscanner/__init__.py
+index 7c2f365a..607fe341 100644
+--- a/giscanner/__init__.py
++++ b/giscanner/__init__.py
+@@ -21,6 +21,8 @@ import os
+ builddir = os.environ.get('UNINSTALLED_INTROSPECTION_BUILDDIR')
+ if builddir is not None:
+     __path__.append(os.path.join(builddir, 'giscanner'))  # type: ignore  # mypy issue #1422
++if not 'CC' in os.environ:
++    os.environ['CC'] = 'gcc'
+ try:
+     from ._version import __version__
+ except ImportError: