diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 1b232d1643..35e52e1e59 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -5929,14 +5929,14 @@ performing parallel computations on multicore machines.")
 (define-public r-affy
   (package
     (name "r-affy")
-    (version "1.78.2")
+    (version "1.80.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "affy" version))
        (sha256
         (base32
-         "0zsr87zsw5rp5rgdiv1bbsi6fx6b7qzlgjirzczky6fmf4dqwgnm"))))
+         "0lsvcv7nprmsh62d0r2v44a5n915crvv1cbj9ba6fdggj7wp8zyk"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-affyio