diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index ecff32e163..dd3980caf4 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -12859,14 +12859,14 @@ All the visualization methods are developed based on ggplot2 graphics.")
 (define-public r-clusterprofiler
   (package
     (name "r-clusterprofiler")
-    (version "4.6.2")
+    (version "4.8.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "clusterProfiler" version))
        (sha256
         (base32
-         "017wqd1nwcrhbpzvhcqc3if0n084dspq7y3fbc5dnik6yi04q0dg"))))
+         "0kr0nmvww7d7fqx6qix5v9brg8h597i4nnfacsazz7gyavdsv7vs"))))
     (properties
      `((upstream-name . "clusterProfiler")))
     (build-system r-build-system)