diff --git a/gnu/packages/icu4c.scm b/gnu/packages/icu4c.scm
index c70871f7e7..717ed277ee 100644
--- a/gnu/packages/icu4c.scm
+++ b/gnu/packages/icu4c.scm
@@ -33,44 +33,20 @@
   #:use-module (guix build-system ant)
   #:use-module (guix build-system gnu))
 
-;; These patches are taken from ICUs 'maint-64' branch and will be included in
-;; 64.3.  The latter patch is needed because many packages use "invalid"
-;; locales which misbehave with ICU 64.2.  See discussion at
-;; <https://lists.gnu.org/archive/html/guix-devel/2019-07/msg00343.html>.
-(define %icu4c-patches
-  (list (origin
-          (method url-fetch)
-          (uri (string-append "https://github.com/unicode-org/icu/commit/"
-                              "7788f04eb9be0d7ecade6af46cf7b9825447763d.patch"))
-          (file-name "icu4c-datetime-regression.patch")
-          (sha256
-           (base32
-            "0gs2sbdfpzwwdjqcqr0c16fw3g7wy3gb1gbgvzs9k1ciw0bhpv4w")))
-        (origin
-          (method url-fetch)
-          (uri (string-append "https://github.com/unicode-org/icu/commit/"
-                              "cfb20862909ff105d4f2c43923c97561bc5a5815.patch"))
-          (file-name "icu4c-locale-mapping.patch")
-          (sha256
-           (base32
-            "0s5psb60aisj6icziblvlp9dqcz56n3887i8ib0yidbjnnrw5b97")))))
-
 (define-public icu4c
   (package
    (name "icu4c")
-   (version "64.2")
+   (version "65.1")
    (source (origin
             (method url-fetch)
             (uri (string-append
-                  "http://download.icu-project.org/files/icu4c/"
-                  version
+                  "https://github.com/unicode-org/icu/releases/download/release-"
+                  (string-map (lambda (x) (if (char=? x #\.) #\- x)) version)
                   "/icu4c-"
                   (string-map (lambda (x) (if (char=? x #\.) #\_ x)) version)
                   "-src.tgz"))
-            (patches %icu4c-patches)
-            (patch-flags '("-p2"))
             (sha256
-             (base32 "0v0xsf14xwlj125y9fd8lrhsaych4d8liv8gr746zng6g225szb2"))))
+             (base32 "0j6r6qqnhfr5iqkx53k63ifkm93kv1kkb7h2mlgd1mnnndk79qsk"))))
    (build-system gnu-build-system)
    ;; When cross-compiling, this package needs a source directory of a
    ;; native-build of itself.